Firstly, it is argued that contemporary medicine (and philosophy of medicine) is in a state of crisis, for, they are incapable to comprehend and to explain the substance of individual's health and the etiology (individual etiogenesis) of contemporary chronic non-infectious diseases (diseases of civilization). Henceforth, following the basic thesis of Prof. Edmund D. Pellegrino (which pushes forward the requirement in "some comprehensive philosophical underpinning for medical ethics"), here is originally advanced a new framework of ontological assumptions, called as 'Absolute Cosmist Wholism'. Further, due to the taken hypothetical-deductive method of cognition, follows the deduction of the theoretical proposals, primarily, - of the basic epistemological principle of CosmoBiotypology. Next, the derived (from the Cosmist ontology and the CosmoBiotypological principle) theoretical proposals emerge; finally, - the bioethical ones, of the Cosmist-Hippocratic essence. It is essential, that the whole philosophical underpinning is built on the Russian cosmist philosophical tradition of pan-unity and active evolution.