The unresolved universal human existential dilemmas, both the Biologically given and Culturally induced, even in today's context of human knowledge and pseudo-knowledge, dictate new paradigms, which unavoidably make a recourse to the past. And Dr. Konstantin Khroutski's BioCosmology, despite its ambiguities and some questionable claims, does offer a much needed today sound analytical beginning, amidst the postmodern confusion, the crisis of creativity and consciousness, and futile attempts to connect the disconnected. Dr. K. Khroutski's "Russian" BioCosmology represents a very intriguing and ambitious neo-Aristotelian model -synthesis of Nature and Culture -all the biological and cultural evolutionary processes of Homo sapiens from the primitive to the most advanced stages of development, with some insights into the future of art of healing and producing culture. We witness a new postmodern renaissance of the Aristotelian metaphysics, philosophy and medical ethics, coming again from a physician-philosopher. It s an attempt to adjust the cultural signification of the last two millennia to the ultimate human physical and cultural possibilities, reaching the desired state of eudomonism in harmony with Cosmos, with the physical and cultural Other, reconciling the ever-seeking homo sapiens with oneself and the restless sapienza. This paper will semiotically dissect Khroutski's paradigm in the light of its own (albeit negated) analytical point of departure-the Aristotelian theories of cosmology, his categories and metaphysics-and its postmodern renditions, arising from the lack of a close textual familiarity and poor translations from Greek. Despite the claims of being an antithesis to the Aristotelian cosmology and universalism, it actually represents its very successful post-modern continuum.